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B21749 Homomorpholine hydrochloride, 98%

CAS Number
Hexahydro-1,4-oxazepine hydrochloride
1,4-Oxazepane hydrochloride

Stock No. Size Price ($) Quantity Availability
B21749-03 1g 254.00
B21749-06 5g 928.00
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Homomorpholine hydrochloride, 98%


Chemical Properties

Formula Weight
Melting point
Storage & Sensitivity
Slightly soluble in water.


Homomorpholine Hydrochloride is a useful synthetic intermediate. It is used to prepare homomorpholine oxazolidinone with antibacterial activities. It is also used to synthesize A2A adenosine receptor antagonists for the treatment of Parkinson's disease.


Hygroscopic. Keep away from oxidizing agents, water/moisture. Store under inert atmosphere. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Ji-Young Kim; Frederick E. Boyer; Allison L. Choy; Michael D. Huband; Paul J. Pagano; J.V.N. Vara Prasad. Synthesis and structure-activity studies of novel homomorpholine oxazolidinone antibacterial agents.Bioorganic & Medicinal Chemistry Letters.200919(2), 550-553.

Zhang, X., et al. Lead Optimization of 4-Acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A Adenosine Receptor Antagonists for the Treatment of Parkinson’s Disease.J. Med. Chem.200851(22), 7099-7110.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code


  • B24073

    3-Chloro-alpha-toluenesulfonyl chloride, 96%
  • L19637

    Isoquinoline-5-carboxylic acid, 96%

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