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B21749 Homomorpholine hydrochloride, 98%

CAS Number
Hexahydro-1,4-oxazepine hydrochloride
1,4-Oxazepane hydrochloride

Stock No. Size Price ($) Quantity Availability
B21749-03 1g 249.00
B21749-06 5g 909.00
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Homomorpholine hydrochloride, 98%


Chemical Properties

Formula Weight
Melting point
Storage & Sensitivity
Hygroscopic. Ambient temperatures.
Slightly soluble in water.


Homomorpholine Hydrochloride is a useful synthetic intermediate. It is used to prepare homomorpholine oxazolidinone with antibacterial activities. It is also used to synthesize A2A adenosine receptor antagonists for the treatment of Parkinson's disease.


Hygroscopic. Keep away from oxidizing agents, water/moisture. Store under inert atmosphere. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Ji-Young Kim; Frederick E. Boyer; Allison L. Choy; Michael D. Huband; Paul J. Pagano; J.V.N. Vara Prasad. Synthesis and structure-activity studies of novel homomorpholine oxazolidinone antibacterial agents.Bioorganic & Medicinal Chemistry Letters.200919(2), 550-553.

Zhang, X., et al. Lead Optimization of 4-Acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A Adenosine Receptor Antagonists for the Treatment of Parkinson’s Disease.J. Med. Chem.200851(22), 7099-7110.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


  • B24073

    3-Chloro-alpha-toluenesulfonyl chloride, 96%
  • L19637

    Isoquinoline-5-carboxylic acid, 96%

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