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122-60-1 - Glycidyl phenyl ether, 99% - 1,2-Epoxy-3-phenoxypropane - 2,3-Epoxypropyl phenyl ether - B21768 - Alfa Aesar

B21768 Glycidyl phenyl ether, 99%

CAS Number
122-60-1
Synonyms
1,2-Epoxy-3-phenoxypropane
2,3-Epoxypropyl phenyl ether

Size Price ($) Quantity Availability
50g 27.81
250g 92.25
1000g 244.80
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Glycidyl phenyl ether, 99%

MDL
MFCD00005133
EINECS
204-557-2

Chemical Properties

Formula
C9H10O2
Formula Weight
150.18
Melting point
3.5°
Boiling Point
244-246°
Flash Point
114°(237°F)
Density
1.110
Refractive Index
1.5310
Solubility
Soluble in water (2.4g/L).

Applications

2-(Phenoxymethyl)oxirane is used in the synthesis of hydrazide-containing inhibitors of HIV-1 integrase.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Zhao, H. et al. Hydrazide-Containing Inhibitors of HIV-1 Integrase.J. Med. Chem.199740(6), 937-941.

E Van den Eeckhout; A De Bruyn; H Pepermans; E L Esmans; I Vryens, J Claereboudt; M Claeys; J E Sinsheimer. Adduct formation identification between phenyl glycidyl ether and 2'-deoxyadenosine and thymidine by chromatography, mass spectrometry and nuclear magnetic resonance spectroscopy.Journal of Chromatography A.1991541(1-2), 317-331.

GHS Hazard and Precautionary Statements

Hazard Statements: H350-H341-H332-H315-H317-H335-H412

May cause cancer. Suspected of causing genetic defects. Harmful if inhaled. Causes skin irritation. May cause an allergic skin reaction. May cause respiratory irritation. Harmful to aquatic life with long lasting effects.

Precautionary Statements: P201-P261-P273-P280-P281-P304+P340-P362-P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2744
Harmonized Tariff Code
2910.90
TSCA
Yes
RTECS
TZ3675000

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