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(S)-(+)-1,2-Propanediol acts as an organic solvent and diluent used in pharmaceutical preparations. It is also used as a chiral synthetic intermediate and substrate for enzyme studies.
For bromoacetoxylation with HBr in acetic acid, see: Org. Synth. Coll., 7, 356 (1990).
Wang, C.; Jiang, H.; Chen, C.; Chen, R.; Xing, W. Solvent effect on hydrogenolysis of glycerol to 1,2-propanediol over Cu-ZnO catalyst. Chem. Eng. J. 2015, 264, 344-350.
Zhu, S.; Gao, X.; Zhu, Y.; Fan, W.; Wang, J.; Li, Y. A highly efficient and robust Cu/SiO2 catalyst prepared by the ammonia evaporation hydrothermal method for glycerol hydrogenolysis to 1,2-propanediol. Catal. Sci. Technol. 2015, 5 (2), 1169-1180.
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