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Reactant used for preparation of fluorescent probes for imaging of tumors in vivo, hypoxia-sensitive fluorescent probes for in vivo real-time imaging of acute ischemia and near IR fluorescent probe for imaging integrin receptor expression.
Koji Miki et. al. High-contrast fluorescence imaging of tumors in vivo using nanoparticles of amphiphilic brush-like copolymers produced by ROMP. Angewandte Chemie. International edition in English., 2011, 50 (29), 6567-6570.
Kazuki Kiyose et. al. Hypoxia-sensitive fluorescent probes for in vivo real-time fluorescence imaging of acute ischemia. Journal of the American Chemical Society, 2010, 132 (45), 15846-15848.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.