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TES plays an important role in production of pH buffers for a biological system. It is used to make zwitterionic buffer solutions in the pH range 6.8-8.2. It is used in molecular biology, diagnosis, cell culture, pharmacy, agrochemical and pharmaceuticals. It is also used in the study of succinate oxidation and one of the components of test yolk buffer medium used in refrigeration of semen and transport.
Biological buffer useful in pH range 7.0 - 8.0: Biochemistry, 5, 467 (1966).
Gupta, B. S.; Taha, M.; Lee, M. J. Interactions of bovine serum albumin with biological buffers, TES, TAPS, and TAPSO in aqueous solutions. Process Biochem. 2013, 48 (11), 1686-1696.
Daub, M. E.; Prudhomme, J.; Roch, K. L.; Vanderwal, C. D. Synthesis and Potent Antimalarial Activity of Kalihinol B. J. Am. Chem. Soc. 2015, 137 (15), 4912-4915.