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2156-56-1 - Sodium dichloroacetate, 97% - Dichloroacetic acid sodium salt - B21827 - Alfa Aesar

B21827 Sodium dichloroacetate, 97%

CAS Number
2156-56-1
Synonyms
Dichloroacetic acid sodium salt

Size Price ($) Quantity Availability
10g 49.44
50g 211.50
250g 774.90
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Sodium dichloroacetate, 97%

MDL
MFCD00070489
EINECS
218-461-3

Chemical Properties

Formula
Cl2CHCO2Na
Formula Weight
150.93
Melting point
197-199° dec.
Sensitivity
Moisture Sensitive
Solubility
Soluble in water.

Applications

Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.

Notes

Moisture sensitive. Incompatible with strong oxidizing agents.

Literature References

Agnoletto, C.; Brunelli, L.; Melloni, E.; Pastorelli, R.; Casciano, F.; Rimondi, E.; Rigolin, G. M.; Cuneo, A.; Secchiero, P.; Zauli, G. The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway. Oncotarget 2015, 6 (4), 2385-2396.

Ji, B.; Tang, P.; Yan, K.; Sun, G. Catalytic actions of alkaline salts in reactions between 1, 2, 3, 4-butanetetracarboxylic acid and cellulose: II. Esterification. Carbohydr. Polym. 2015, 132, 228-236.

GHS Hazard and Precautionary Statements

Hazard Statements: H341-H315-H319-H335-H303

Suspected of causing genetic defects. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Precautionary Statements: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2915.40
TSCA
No

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