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75621-03-3 - CHAPS, 98+% - 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate - B21927 - Alfa Aesar

B21927 CHAPS, 98+%

CAS Number
75621-03-3
Synonyms
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Size Price ($) Quantity Availability
1g 52.70
5g 182.00
25g 662.00
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CHAPS, 98+%

MDL
MFCD00012116

Chemical Properties

Formula
C32H58N2O7S
Formula Weight
614.88
Melting point
156-158° dec.
Solubility
Slightly soluble in water.

Applications

Buffer; zwitterionic nondenaturing detergent for solubilizing membrane proteinsCHAPS is used in the laboratory to dissolve biological macromolecules such as proteins. It acts as a non-denaturing solvent used in purification of membrane proteins. It is also useful in conjunction with nonionic detergents like Triton X-100. Further, it is used as a non-denaturing zwitterionic detergent for membrane biochemistry.

Notes

Store in a cool. Incompatible with oxidizing agent, strong acid and bases.

Literature References

Rodi, P. M.; Gianello, M. D. B.; Corregido, M. C.; Gennaro, A. M. Comparative study of the interaction of CHAPS and Triton X-100 with the erythrocyte membrane. Biochim. Biophys. Acta 2014, 1838 (3), 859-866.

Ghosh, A.; Saha, R.; Saha, B. Effect of CHAPS and CPC micelles on Ir(III) catalyzed Ce(IV) oxidation of aliphatic alcohols at room temperature and pressure. J. Mol. Liq. 2014, 196, 223-237.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2924.29
TSCA
No

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