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4-chloro-2,6-dimethylaniline was chosen as a substrate of medium in palladium-catalyzed cyanations of aryl chlorides.
P. B. M. W. M. Timmermans,; P. A. van Zwieten,; W. N. Speckamp. 2-(Arylimino)imidazolidines; synthesis and hypotensive activity. Recueil des Travaux Chimiques des Pays-Bas. 1978, 97(2), 1-56, 1978.
Thomas Schareina,; Ralf Jackstell,; Thomas Schulz. Increasing the Scope of Palladium-Catalyzed Cyanations of Aryl Chlorides. Advanced Synthesis & Catalysis. 2009, 351 (4), 643-648.
Hazard Statements: H301-H315-H319-H335
Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.