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959-23-9 - 4'-Methoxychalcone, 97% - 2-Benzylidene-4'-methoxyacetophenone - B22158 - Alfa Aesar

B22158 4'-Methoxychalcone, 97%

CAS Number
959-23-9
Synonyms
2-Benzylidene-4'-methoxyacetophenone

Size Price ($) Quantity Availability
5g 19.80
25g 62.00
100g 207.00
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4'-Methoxychalcone, 97%

MDL
MFCD00008407
EINECS
213-495-5

Chemical Properties

Formula
C16H14O2
Formula Weight
238.29
Melting point
101-103°
Solubility
Soluble in dichloromethane and methanol. Insoluble in water.

Applications

4-Methoxychalcone is used as a precursor to prepare 3-(4-methoxy-phenyl)-3-morpholin-4-yl-1-phenyl-propan-1-one by reacting with morpholine in presence of heptanes as solvent.

Notes

Keep the container tightly closed in a dry and well-ventilated place. Incompatible withstrong oxidizing agents.

Literature References

Lee, D. S.; Li, B.; Im, N. K.; Kim, Y. C.; Jeong, G. S. 4,2',5'-Trihydroxy-4'-methoxychalcone from Dalbergia odorifera exhibits anti-inflammatory properties by inducing heme oxygenase-1 in murine macrophages. Int. Immunopharmacol. 2013, 16 (1), 114-121.

Lim, J.; Lee, S. H.; Cho, S.; Lee, I. S.; Kang, B. Y.; Choi, H. J. 4-methoxychalcone enhances cisplatin-induced oxidative stress and cytotoxicity by inhibiting the Nrf2/ARE-mediated defense mechanism in A549 lung cancer cells. Mol. Cells 2013, 36 (4), 340-346.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
644640
Harmonized Tariff Code
2914.50
TSCA
No

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