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Hydroxylamine is a reactant used for the preparation of hydroxyaminoguanidines which are anti-cancer agents, carboxamide derivatives of ofloxacin and human immunodeficiency virus (HIV) integrase inhibitors. It reacts with chlorosulfonic acid to give hydroxylamine-O-sulfonic acid, a useful reagent in the synthesis of caprolactam. It is commonly used as a reducing agent in myriad of organic and inorganic reactions. It acts as an antioxidant for fatty acids. It is widely used to prepare oximes, an important functional group.
Heil, J.; Liu, S.; Vereecken, H.; Brüggemann, N. Abiotic nitrous oxide production from hydroxylamine in soils and their dependence on soil properties. Soil Biol. Biochem. 2015, 84, 107-115.
Alibeik, M. A.; Moaddeli, A. Multi-component one-pot reaction of aldehyde, hydroxylamine and sodium azide catalyzed by Cu-MCM-41 nanoparticles: a novel method for the synthesis of 5-substituted 1 H-tetrazole derivatives. New J. Chem. 2015, 39 (3), 2116-2122.
Hazard Statements: H290-H302-H312-H315-H318-H317-H351-H335-H373
May be corrosive to metals. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye damage. May cause an allergic skin reaction. Suspected of causing cancer. May cause respiratory irritation. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P201-P280-P305+P351+P338-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.