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2,6-Diaminopimelic acid is used as a constituent of proteoglycans. It is used as a component of bacterial cell wall.
Hanson, R. L.; Johnston, R. M.; Goldberg, S. L.; Parker, W. L.; Goswami, A.Enzymatic Preparation of an R-Amino Acid Intermediate for a γ-Secretase Inhibitor. Org. Process Res. Dev. 2013, 17 (4), 693-700.
Wyckoff, T. J.; Taylor, J. A.; Salama, N. R. Beyond growth: novel functions for bacterial cell wall hydrolases. Trends Microbiol. 2012, 20 (11), 540-547.
Stegmann, E.; Frasch, H- J.; Kilian, R.; Pozzi, R. Self-resistance mechanisms of actinomycetes producing lipid II-targeting antibiotics. Int. J. Med. Microbiol. 2015, 305 (2), 190-195.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant