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138-41-0 - 4-Sulfamoylbenzoic acid, 96% - 4-(Aminosulfonyl)benzoic acid - 4-Carboxybenzenesulfonamide - B22449 - Alfa Aesar

B22449 4-Sulfamoylbenzoic acid, 96%

CAS Number
138-41-0
Synonyms
4-(Aminosulfonyl)benzoic acid
4-Carboxybenzenesulfonamide

Size Price ($) Quantity Availability
50g 37.90
250g 110.21
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4-Sulfamoylbenzoic acid, 96%

MDL
MFCD00007938
EINECS
205-327-4

Chemical Properties

Formula
C7H7NO4S
Formula Weight
201.20
Melting point
ca 285° dec.
Solubility
Insoluble in water.

Applications

Sulfamoylbenzoic acid is a moiety of sulfamyl diuretics or antihypertensive. It is used as an antiviral and an intermediate for the manufacture of frusemide which used as a diuretic and as an antihypertensive.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Ahamindra Jain.; Shaw G. Huang.; George M. Whitesides. 1,1'-Thiocarbonyldi-2,2'-pyridone. Lack of Effect of the Length of Oligoglycine- and Oligo(ethylene glycol)-Derived para-Substituents on the Affinity of Benzenesulfonamides for Carbonic Anhydrase II in Solution. J. Am. Chem. Soc. 1994, 116, (12), 5057-5062.

George B. Sigal.; George M. Whitesides. Benzenesulfonamide-peptide conjugates as probes for secondary binding sites near the active site of carbonic anhydrase. Bioorganic & Medicinal Chemistry Letters.1996, 6, (5), 559-564.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1876
Beilstein
1875393
Harmonized Tariff Code
2935.00
TSCA
Yes
RTECS
DH6820000

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