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B22449 4-Sulfamoylbenzoic acid, 96%

CAS Number
138-41-0
Synonyms
4-(Aminosulfonyl)benzoic acid
4-Carboxybenzenesulfonamide

Stock No. Size Price ($) Quantity Availability
B22449-18 50g 37.90
B22449-30 250g 110.21
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4-Sulfamoylbenzoic acid, 96%

MDL
MFCD00007938
EINECS
205-327-4

Chemical Properties

Formula
C7H7NO4S
Formula Weight
201.20
Melting point
ca 285° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Insoluble in water.

Applications

Sulfamoylbenzoic acid is a moiety of sulfamyl diuretics or antihypertensive. It is used as an antiviral and an intermediate for the manufacture of frusemide which used as a diuretic and as an antihypertensive.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Ahamindra Jain.; Shaw G. Huang.; George M. Whitesides. 1,1'-Thiocarbonyldi-2,2'-pyridone. Lack of Effect of the Length of Oligoglycine- and Oligo(ethylene glycol)-Derived para-Substituents on the Affinity of Benzenesulfonamides for Carbonic Anhydrase II in Solution. J. Am. Chem. Soc. 1994, 116, (12), 5057-5062.

George B. Sigal.; George M. Whitesides. Benzenesulfonamide-peptide conjugates as probes for secondary binding sites near the active site of carbonic anhydrase. Bioorganic & Medicinal Chemistry Letters.1996, 6, (5), 559-564.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1876
Beilstein
1875393
Harmonized Tariff Code
2935.90
TSCA
Yes
RTECS
DH6820000

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