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Hydroquinone-O,O'-diacetic acid is used as an organic chemical synthesis intermediate.
Richard T.Pon; Shuyuan Yu. Hydroquinone-O,O?-diacetic acid (Q-linker) as a replacement for succinyl and oxalyl linker arms in solid phase oligonucleotide synthesis. Nucl. Acids Res. 1997, 25,(18), 3629-3635.
R. T. Pon; S.Yu; Z.Guo; X.Yang; Y.S.Sanghvi. Reusable solid-phase supports for oligonucleotide synthesis using hydroquinone-O,O'-diacetic acid (Q-Linker). Nucleosides and Nucleotides. 1999, 18,(6-7), 1237-1238.
Linker for solid-phase oligonucleotide synthesis: cleavage from the support occurs ca 30x more rapidly than with the conventional succinic acid linker: Nucleic Acids Res., 25, 3629; Bioconjugate Chem., 10, 1051 (1999).
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.