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2245-53-6 - Hydroquinone-O,O'-diacetic acid, 98% - Q-Linker - B22645 - Alfa Aesar

B22645 Hydroquinone-O,O'-diacetic acid, 98%

CAS Number
2245-53-6
Synonyms
Q-Linker

Size Price ($) Quantity Availability
5g 39.40
25g 133.00
100g 414.00
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Hydroquinone-O,O'-diacetic acid, 98%

MDL
MFCD00016816
EINECS
218-834-0

Chemical Properties

Formula
C10H10O6
Formula Weight
226.19
Melting point
ca 255° dec.
Solubility
Slightly soluble in water.

Applications

Hydroquinone-O,O'-diacetic acid is used as an organic chemical synthesis intermediate.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Richard T.Pon; Shuyuan Yu. Hydroquinone-O,O?-diacetic acid (‘Q-linker’) as a replacement for succinyl and oxalyl linker arms in solid phase oligonucleotide synthesis. Nucl. Acids Res. 1997, 25,(18), 3629-3635.

 

R. T. Pon; S.Yu; Z.Guo; X.Yang; Y.S.Sanghvi. Reusable solid-phase supports for oligonucleotide synthesis using hydroquinone-O,O'-diacetic acid (“Q-Linker”). Nucleosides and Nucleotides. 1999, 18,(6-7), 1237-1238.

Linker for solid-phase oligonucleotide synthesis: cleavage from the support occurs ca 30x more rapidly than with the conventional succinic acid linker: Nucleic Acids Res., 25, 3629; Bioconjugate Chem., 10, 1051 (1999).

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1984454
Harmonized Tariff Code
2918.99
TSCA
Yes

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