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3-Chloro-2-methylpropene has been used as reactant in the synthesis of cyclobutanone. It is used as an intermediate in the production of plastics, pharmaceuticals and other organic chemicals.
Po C.Chan; Joseph K.Haseman; Gary A.Boorman; James Huff; Allan G.Manus; Rechard H.Cardy. Forestomach lesions in rats and mice administered 3-chloro-2-methylpropene by gavage for two years. Cancer Res. 1986, 46,6349-6352.
D.A.C.Compton; S.C.Hsi; H.H.Mantsch; W.F.Murphy. The vibrational spectrum, normal coordinate analysis and conformational equilibrium of 3-chloro-2-methylpropene. Journal of Raman Spectroscopy. 1982, 13,(1), 30-37.
Hazard Statements: H225-H302-H314-H317-H332-H335-H350
Highly flammable liquid and vapour. Harmful if swallowed. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Harmful if inhaled. May cause respiratory irritation. May cause cancer.
Precautionary Statements: P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P272-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P372-P374-P380-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Use personal protective equipment as required. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Explosion risk in case of fire. Fight fire with normal precautions from a reasonable distance. Evacuate area. Dispose of contents/ container to an approved waste disposal plant