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3-Chloro-2-methylpropene has been used as reactant in the synthesis of cyclobutanone. It is used as an intermediate in the production of plastics, pharmaceuticals and other organic chemicals.
Po C.Chan; Joseph K.Haseman; Gary A.Boorman; James Huff; Allan G.Manus; Rechard H.Cardy. Forestomach lesions in rats and mice administered 3-chloro-2-methylpropene by gavage for two years. Cancer Res. 1986, 46,6349-6352.
D.A.C.Compton; S.C.Hsi; H.H.Mantsch; W.F.Murphy. The vibrational spectrum, normal coordinate analysis and conformational equilibrium of 3-chloro-2-methylpropene. Journal of Raman Spectroscopy. 1982, 13,(1), 30-37.
Hazard Statements: H225-H302-H332-H314-H317
Highly flammable liquid and vapour. Harmful if swallowed. Harmful if inhaled. Causes severe skin burns and eye damage. May cause an allergic skin reaction.
Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.