I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
1,2,3,4-Tetrahydroquinoline is used as an antioxidant and corrosion inhibitor. It is an active component in various dyes.
2-Metallation can be effected in a one-pot sequence via the Li carbamate: J. Chem. Soc., Perkin 1, 17 (1989); cf Indole, A14427.
1,2,3,4-Tetrahydroquinoline derivatives are oxidized to N-hydroxy lactams by H2O2 in the presence of tungstate ion: J. Org. Chem., 55, 1744 (1990):
Liu, J.; Liu, F.; Zhu, Y.; Ma, X.; Jia, X. Oxidative Povarov Reaction via sp3 C-H Oxidation of N-Benzylanilines Induced by Catalytic Radical Cation Salt: Synthesis of 2,4-Diarylquinoline Derivatives. Org. Lett. 2015, 17 (6), 1409-1412.
Jiang, H. Y.; Zheng, X. X. Phosphine-functionalized ionic liquid-stabilized rhodium nanoparticles for selective hydrogenation of aromatic compounds. Appl. Catal., A 2015, 499, 118-123.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.