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98437-23-1 - Benzo[b]thiophene-2-boronic acid, 98% - Thianaphthene-2-boronic acid - B22835 - Alfa Aesar

B22835 Benzo[b]thiophene-2-boronic acid, 98%

CAS Number
98437-23-1
Synonyms
Thianaphthene-2-boronic acid

Size Price ($) Quantity Availability
1g 24.80
5g 70.90
25g 230.00
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Benzo[b]thiophene-2-boronic acid, 98%

MDL
MFCD01075674

Chemical Properties

Formula
C8H7BO2S
Formula Weight
178.02
Melting point
ca 255°
Solubility
Insoluble in water.

Applications

Benzo[b]thiophene-2-boronic acid is used in the synthesis of phosphorescent sensor for quantification of copper(II) ion, UV promoted phenanthridine syntheses, Preparation of CYP11B1 inhibitors for treatment of cortisol dependent diseases, PDE4 inhibitors, Suzuki-Miyaura cross-coupling reactions.

Notes

Store in cool, dry conditions in a sealed container. Incompatible with oxidizing agents.

Literature References

Frédéric J.J. Bihel; Hélène Justiniano; Martine Schmitt; Malik Hellal; Mohamed A. Ibrahim; Claire Lugnier; Jean-Jacques Bourguigno. New PDE4 inhibitors based on pharmacophoric similarity between papaverine and tofisopam. Bioorganic & Medicinal Chemistry Letters. 2011, 21 (21), 6567-6572.

Partha S. Banerjee; Edison S. Zuniga; Iwao Ojima; Isaac S. Carrico. Targeted and armed oncolytic adenovirus via chemoselective modification. Bioorganic & Medicinal Chemistry Letters. 2011, 21, (17), 4985-4988.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1637924
Harmonized Tariff Code
2934.99
TSCA
No

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