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B22877 4',7-Dihydroxyisoflavone, 97%

CAS Number
486-66-8
Synonyms
Daidzein

Stock No. Size Price ($) Quantity Availability
B22877-03 1g 64.90
B22877-06 5g 229.00
B22877-14 25g 840.00
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4',7-Dihydroxyisoflavone, 97%

MDL
MFCD00016954
EINECS
207-635-4

Chemical Properties

Formula
C15H10O4
Formula Weight
254.24
Melting point
328-332° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).

Applications

4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Literature References

Eun Jeong Choi; Gun-Hee Kim. Hepatoprotective effects of daidzein against 7,12-dimetylbenz[a]anthracene-induced oxidative stress in mice. International Journal of Molecular Medicine. 2009, 23,(5), 659-664.

 

N.Sathyamoorthy; T.T.Wang; J.M.Phang. Stimulation of pS2 expression by diet-derived compounds. Cancer Research. 1994, 54,(4), 957-961.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319

Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362

Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse.

Other References

Merck
14,2801
Beilstein
231523
Harmonized Tariff Code
2932.99
TSCA
No
RTECS
DJ3100040

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