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486-66-8 - 4',7-Dihydroxyisoflavone, 97% - Daidzein - B22877 - Alfa Aesar

B22877 4',7-Dihydroxyisoflavone, 97%

CAS Number
486-66-8
Synonyms
Daidzein

Size Price ($) Quantity Availability
1g 63.10
5g 224.00
25g 823.00
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4',7-Dihydroxyisoflavone, 97%

MDL
MFCD00016954
EINECS
207-635-4

Chemical Properties

Formula
C15H10O4
Formula Weight
254.24
Melting point
328-332° dec.
Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).

Applications

4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Literature References

Eun Jeong Choi; Gun-Hee Kim. Hepatoprotective effects of daidzein against 7,12-dimetylbenz[a]anthracene-induced oxidative stress in mice. International Journal of Molecular Medicine. 2009, 23,(5), 659-664.

 

N.Sathyamoorthy; T.T.Wang; J.M.Phang. Stimulation of pS2 expression by diet-derived compounds. Cancer Research. 1994, 54,(4), 957-961.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2801
Beilstein
231523
Harmonized Tariff Code
2932.99
TSCA
No
RTECS
DJ3100040

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