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Methoxyacetic acid is used in zebrafish embryotoxicity test to evaluate chemical toxicity after exposure of the complete vertebrate embryo during embryogenesis. It is also used in industry as gelling, viscosity and stabilizer reagent.
Reacts with thionyl chloride on prolonged refluxing, to give chloromethyl methyl ether, reportedly free from the highly carcinogenic bis(chloromethyl)ether: Synthesis, 727 (1984).
świechowicz, B. S.; Szymczak, W.; Budziszewska, B.; Starek, A. Testicular effect of a mixture of 2-methoxyethanol and 2-ethoxyethanol in rats. Pharmacol. Rep. 2015, 67 (2), 289-293.
Grala, A.; Pietkiewicz, M. W.; Wojewódzka, A.; Dabergut, M.; Justyniak, I.; Lewin?ski, J. Structural Diversity of Ethylzinc Carboxylates. Organometallics 2015, 34 (20), 4959-4964.
Hazard Statements: H302-H314-H360
Harmful if swallowed. Causes severe skin burns and eye damage. May damage fertility or the unborn child.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.