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60-27-5 - Creatinine, 98% - 2-Imino-1-methylimidazolidin-4-one - B23097 - Alfa Aesar

B23097 Creatinine, 98%

CAS Number
60-27-5
Synonyms
2-Imino-1-methylimidazolidin-4-one

Size Price ($) Quantity Availability
10g 21.60
50g 72.20
250g 243.00
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Creatinine, 98%

MDL
MFCD00059730
EINECS
200-466-7

Chemical Properties

Formula
C4H7N3O
Formula Weight
113.12
Melting point
ca 255° dec.
Solubility
Soluble in water (90 mg/ml at 20°C), alcohol (slightly), and ethanol (slightly). Insoluble in acetone, and chloroform.

Applications

Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function. It is a substrate for creatininase.

Notes

Store in a cool, dry conditions, in well sealed conditions. Store away from oxidizing agents.

Literature References

Cockcroft D.W.; Gault M.H. Prediction of Creatinine Clearance from Serum Creatinine. Nephron. 1976, 17, 31-41.

Schwartz GJ; Brion LP; Spitzer A. The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Europe PMC. 1987, 34 (3), 571-590.

Reacts with aromatic aldehydes in a route to derivatives of N-methylphenylalanine: Org. Synth. Coll., 3, 586 (1955):

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2569
Beilstein
112061
Harmonized Tariff Code
2933.29
TSCA
Yes

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