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Beta-Propiolactone is widely used as a sterilizing and sporicidal agent, which is used to sterilize blood plasma, vaccines, tissue grafts, surgical instruments and enzymes. It finds an application in the manufacturing of acrylic acid and its esters. It is utilized as an intermediate in the synthesis of synthetic compounds.
Goodman, C. H.; Russell, B. J.; Velez, J. O.; Laven, J. J.; Bagarozzi, Jr. D. A.; Moon, J. L.; Bedi, K.; Johnson, B. W. Production of a Sindbis/Eastern Equine Encephalitis chimeric virus inactivated cell culture antigen. J. Virol. Methods. 2015, 223, 19-24.
Pawar, S.D.; Murtadak, V. B.; Kale, S. D.; Shinde, P. V.; Parkhi, S. S. Evaluation of different inactivation methods for high and low pathogenic avian influenza viruses in egg-fluids for antigen preparation. J. Virol. Methods. 2015, 222, 28-33.
Hazard Statements: H227-H315-H319-H330-H350
Combustible liquid. Causes skin irritation. Causes serious eye irritation. Fatal if inhaled. May cause cancer.
Precautionary Statements: P201-P202-P210-P235-P260-P264b-P271-P280i-P281-P284-P302+P352-P304+P340-P305+P351+P338-P308+P313-P310-P332+P313-P337+P313-P362-P370+P378q-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. Wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Immediately call a POISON CENTER or doctor/physician. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant