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1,2-Benzisoxazole derivative zonisamide is a novel antiepileptic drug and is effective for the treatment of partial seizures. 1,2-Benzisoxazole is a potential substrates of rabbit liver aldehyde oxidase. It is used to produce 5-nitro-benzo[d]isoxazole. It is involved in manufacturing medicines ( antiepileptics and antipsychotics).
D H Peters; E M Sorkin. Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs.1993, 45, (5), 760-787.
W Gristwood; K Wilson. Kinetics of some benzothiazoles, benzoxazoles, and quinolines as substrates and inhibitors of rabbit liver aldehyde oxidase. Xenobiotica.1988, 18, (8), 949-954.
Hazard Statements: H227
Precautionary Statements: P210-P280-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant