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271-95-4 - 1,2-Benzisoxazole, 97% - Indoxazene - B23400 - Alfa Aesar

B23400 1,2-Benzisoxazole, 97%

CAS Number
271-95-4
Synonyms
Indoxazene

Size Price ($) Quantity Availability
1g 20.40
5g 59.10
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1,2-Benzisoxazole, 97%

MDL
MFCD00005852
EINECS
205-983-1

Chemical Properties

Formula
C7H5NO
Formula Weight
119.12
Boiling Point
90-92°/15mm
Flash Point
86°(186°F)
Density
1.169
Refractive Index
1.5620
Sensitivity
Light Sensitive
Solubility
Soluble in water. 4.1 mg/mL in water at 25°C

Applications

1,2-Benzisoxazole derivative zonisamide is a novel antiepileptic drug and is effective for the treatment of partial seizures. 1,2-Benzisoxazole is a potential substrates of rabbit liver aldehyde oxidase. It is used to produce 5-nitro-benzo[d]isoxazole. It is involved in manufacturing medicines ( antiepileptics and antipsychotics).

Notes

Light Sensitive. Store at 4°C. Store in the dark. Incompatible with light and oxidizing agents.

Literature References

D H Peters; E M Sorkin. Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs.1993, 45, (5), 760-787.

W Gristwood; K Wilson. Kinetics of some benzothiazoles, benzoxazoles, and quinolines as substrates and inhibitors of rabbit liver aldehyde oxidase. Xenobiotica.1988, 18, (8), 949-954.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H315-H319-H335

Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P210u-P261-P280a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2154
Harmonized Tariff Code
2934.99
TSCA
No

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