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4-Ethylphenol is suitable for use in the determination of 4-ethylguaiacol and 4-ethylphenol in the aroma of red wines using headspace-solid-phase microextraction method. It is a chemical reagent used in the synthesis of 5-HT1A receptor agonists endowed with antinociceptive activity in vivo. It is also used in the preparation of isopropylamides as potent and noncovalent proteosome inhibitors.
N Martorell; M P Martí; M Mestres; O Busto; J Guasch. Determination of 4-ethylguaiacol and 4-ethylphenol in red wines using headspace-solid-phase microextraction-gas chromatography. Journal of Chromatography A.2009, 1216, (15), 3023-3030.
Margarita Valhondo; Isabel Marco; Mar Martín-Fontecha; Henar Vázquez-Villa; José A. Ramos; Reinhard Berkels; Thomas Lauterbach; Bellinda Benhamú and María L. López-Rodríguez. New Serotonin 5-HT1A Receptor Agonists Endowed with Antinociceptive Activity in Vivo. J. Med. Chem.2013, 56, (20), 7851-7861.
Hazard Statements: H312-H332-H314-H318
Harmful in contact with skin. Harmful if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.