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DL-Pipecolinic acid is used as a diagnostic marker of pyridoxine-dependent epilepsy. It acts as a ligand in copper-catalyzed approach for P-arylation of organophosphorus compounds. It is used as organocatalyst and novel substrate in organic synthesis.
Isabelle M Medana; Nicholas P J Day; Houta Salahifar-Sabet; Roland Stocker; George Smythe; Lloyd Bwanaisa; Alfred Njobvu; Kondwani Kayira; Gareth D H Turner; Terrie E Taylor; Nicholas H Hunt. Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. Journal of Infectious Diseases. 2003, 188, (6), 844-849.
Plecko B; Hikel C; Korenke GC; Schmitt B; Baumgartner M; Baumeister F; Jakobs C; Struys E; Erwa W; Stöckler-Ipsiroglu S. Pipecolic acid as a diagnostic marker of pyridoxine-dependent epilepsy. Neuropediatrics. 2005, 36, (3), 200-205.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.