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3-Methoxybenzoyl chloride is used in the synthesis of 2-arylbenzofuran-based molecules that act against Alzheimers disease, combatting symptoms. In addition, it aids in the optimization of dihydropyrrolopyrimidine inhibitors against PI3K (phosphoinositide 3-kinase) resulting in tumor growth inhibition.
Stefano Rizzoa; Andrea Tarozzi; Manuela Bartolini; Gregory Da Costa; Alessandra Bisi; Silvia Gobbi; Federica Belluti; Alessia Ligresti; Marco Allarà; Jean-Pierre Monti; Vincenza Andrisano; Vincenzo Di Marzo; Patrizia Hrelia; Angela Rampa. 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents. European Journal of Medicinal Chemistry. 2012, 58, 519-532.
Hatsuo Kawada; Hirosato Ebiike; Masao Tsukazaki; Mitsuaki Nakamura; Kenji Morikami; Kiyoshi Yoshinari; Miyuki Yoshida; Kotaro Ogawa; Nobuo Shimma; Takuo Tsukuda; Jun Ohwada. Bioorganic & Medicinal Chemistry Letters. 2013, 23, 673-678.
Hazard Statements: H227-H314-H318
Combustible liquid. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P201-P280a-P304+P340-P405-P501a
Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.