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8-Nitroquinoline is used in the preparation of bisubstituted phenoxy-6-methoxy-8-aminoquinoline. It is used to prepare furazano [3,4-h] quinoline.
M Hasegawa; T Takabatake; T Miyazawa. [Formations and reactions of aromatic furazan compounds]. YAKUGAKU ZASSHI . 2001, 121, (6), 379-393.
C Chen; X Y Zheng; H Z Guo. [Studies on the tissue schizonticide of malaria parasite: synthesis of derivatives of 2-substituted phenoxyprimaquine, 4-methylprimaquine and quinoxaline]. Yao xue xue bao = Acta pharmaceutica Sinica. 1992, 27, (6), 418-422.
Hazard Statements: H315-H319-H341-H351-H335
Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects. Suspected of causing cancer. May cause respiratory irritation.
Precautionary Statements: P201-P261-P280-P305+P351+P338-P405-P501a
Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.