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8-Nitroquinoline is used in the preparation of bisubstituted phenoxy-6-methoxy-8-aminoquinoline. It is used to prepare furazano [3,4-h] quinoline.
M Hasegawa; T Takabatake; T Miyazawa. [Formations and reactions of aromatic furazan compounds]. YAKUGAKU ZASSHI . 2001, 121, (6), 379-393.
C Chen; X Y Zheng; H Z Guo. [Studies on the tissue schizonticide of malaria parasite: synthesis of derivatives of 2-substituted phenoxyprimaquine, 4-methylprimaquine and quinoxaline]. Yao xue xue bao = Acta pharmaceutica Sinica. 1992, 27, (6), 418-422.
Hazard Statements: H315-H319-H335-H341-H351
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Suspected of causing genetic defects. Suspected of causing cancer.
Precautionary Statements: P201-P202-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. If skin irritation occurs: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant