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5-Bromo-2,2-difluoro-1,3- benzodioxole is used as a precursor in organic synthesis. It is used to prepare 5-bromo-2,2-difluoro-1,3-benzodioxole-4-carboxylic acid. It serves as an intermediate in active pharmaceutical ingredients, agrochemicals and in dyestuff field.
Genet, J. P.; Ayad, T.; Ratovelomanana-Vidal, V. Electron-Deficient Diphosphines: The Impact of DIFLUORPHOS in Asymmetric Catalysis. Chem. Rev. 2014, 114 (5), 2824-2880.
Leroux, F. R.; Simon, R.; Nicod, N. A Highly Efficient Low Temperature Modification of the Classical Ullmann Reaction. Lett. Org. Chem. 2006, 3 (12), 948-954.
Hazard Statements: H315-H319
Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313
Wear protective gloves and eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: