2-Bromopropionyl chloride is a reagent that is used in the preparation of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase. It is also used in the synthesis of 2-aminopropionyl polystyrene resin by Friedel Crafts reaction.
Katja Jankova, et al. Synthesis of poly(styrene-b-isobutylene-b-styrene) triblock copolymer by ATRP.Polym. Bull.,1998,41(6), 639-644.
Su-Sun. Wang. Solid phase synthesis of protected peptides via photolytic cleavage of the .alpha.-methylphenacyl ester anchoring linkage.J. Org. Chem.,1976,41(20), 3258-3261.
Hazard Statements: H226-H314-H318
Flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P201-P280a-P304+P340-P405-P501a
Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.