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7148-74-5 - 2-Bromopropionyl chloride, 98% - B23662 - Alfa Aesar

B23662 2-Bromopropionyl chloride, 98%

CAS Number
7148-74-5
Synonyms

Size Price ($) Quantity Availability
10g 55.62
50g 198.00
250g 494.10
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2-Bromopropionyl chloride, 98%

MDL
MFCD00000711
EINECS
230-466-2

Chemical Properties

Formula
CH3CHBrCOCl
Formula Weight
171.43
Boiling Point
131-133°
Flash Point
51°(125°F)
Density
1.700
Refractive Index
1.4780
Solubility
Reacts with water.

Applications

2-Bromopropionyl chloride is a reagent that is used in the preparation of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase. It is also used in the synthesis of 2-aminopropionyl polystyrene resin by Friedel Crafts reaction.

Notes

Protect from water/moisture, bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Keep away from ignition sources. Protect from electrostatic charges.

Literature References

Katja Jankova, et al. Synthesis of poly(styrene-b-isobutylene-b-styrene) triblock copolymer by ATRP.Polym. Bull.,1998,41(6), 639-644.

Su-Sun. Wang. Solid phase synthesis of protected peptides via photolytic cleavage of the .alpha.-methylphenacyl ester anchoring linkage.J. Org. Chem.,1976,41(20), 3258-3261.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318-H226

Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapour.

Precautionary Statements: P210-P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
773800
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
No

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