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It is used in organic synthesis for aromatic nucleophilic N-N exchange reaction. tert-Butylhydrazine Hydrochloride is also used in the preparation of insect growth regulator. tert-Butylhydrazine hydrochloride was used in the synthesis of diphosphinohydrazines, 5-amino-1-tert-butyl-3-(p-chlorophenyl)-4-cyanopyrazole and 1,3,4,5-tetrasubstituted pyrazole derivatives.
Clarissa P. Frizzo, et al. Ionic liquid effects on the reaction of β-enaminones and tert-butylhydrazine and applications for the synthesis of pyrazoles.Catal. Commun..,2009,10(15), 1967-1970.
Yoshihiro Sawada, et al. Synthesis and insecticidal activity of benzoheterocyclic analogues of N?-benzoyl-N-(tert-butyl)benzohydrazide: Part 3. Modification of N-tert-butylhydrazine moiety.Pest Management Science.,2003,59(1), 49-57.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.