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93-60-7 - Methyl nicotinate, 99% - Methyl pyridine-3-carboxylate - Nicotinic acid methyl ester - B23908 - Alfa Aesar

B23908 Methyl nicotinate, 99%

CAS Number
93-60-7
Synonyms
Methyl pyridine-3-carboxylate
Nicotinic acid methyl ester

Size Price ($) Quantity Availability
100g 30.00
250g 43.00
500g 79.90
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Methyl nicotinate, 99%

MDL
MFCD00006388
EINECS
202-261-8

Chemical Properties

Formula
C7H7NO2
Formula Weight
137.14
Melting point
40-44°
Boiling Point
208-210°
Flash Point
95°(203°F)
Solubility
Soluble in water at 20°C 48 g/L. Soluble in alcohol, chloroform and ethyl acetate. Solubility in methanol (almost transparency).

Applications

Used as a rubefacient, topical vasodilator used to test the efficacy of skin protection compounds (i.e. products designed to provide barriers to chemical warfare agents) and used as a flavoring agent. It is a useful synthetic intermediate. It can be used to prepare biarylcarboxamide inhibitors of phosphodiesterase IV and tumor necrosis factor-α in treatment of rheumatoid arthritis.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Qin Y, et al. Synthesis and antifungal evaluation of (1,2,3-triazol-4-yl)methyl nicotinate chitosan.Int J Biol Macromol.,2013,6158-62.

Pabst H, et al. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomized controlled trial.Phytother Res.,2013,27(6), 811-7.

GHS Hazard and Precautionary Statements

Hazard Statements: H319-H317

Causes serious eye irritation. May cause an allergic skin reaction.

Precautionary Statements: P262-P280g-P305+P351+P338

Do not get in eyes, on skin, or on clothing. Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Merck
14,6100
Beilstein
113951
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
QT1925000

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