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B23908 Methyl nicotinate, 99%

CAS Number
93-60-7
Synonyms
Methyl pyridine-3-carboxylate
Nicotinic acid methyl ester

Stock No. Size Price ($) Quantity Availability
B23908-22 100g 29.30
B23908-30 250g 44.80
B23908-36 500g 82.00
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Methyl nicotinate, 99%

MDL
MFCD00006388
EINECS
202-261-8

Chemical Properties

Formula
C7H7NO2
Formula Weight
137.14
Melting point
40-44°
Boiling Point
208-210°
Flash Point
95°(203°F)
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water at 20°C 48 g/L. Soluble in alcohol, chloroform and ethyl acetate. Solubility in methanol (almost transparency).

Applications

Used as a rubefacient, topical vasodilator used to test the efficacy of skin protection compounds (i.e. products designed to provide barriers to chemical warfare agents) and used as a flavoring agent. It is a useful synthetic intermediate. It can be used to prepare biarylcarboxamide inhibitors of phosphodiesterase IV and tumor necrosis factor-α in treatment of rheumatoid arthritis.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Qin Y, et al. Synthesis and antifungal evaluation of (1,2,3-triazol-4-yl)methyl nicotinate chitosan.Int J Biol Macromol.,2013,6158-62.

Pabst H, et al. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomized controlled trial.Phytother Res.,2013,27(6), 811-7.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H500

Causes skin irritation. Causes serious eye irritation. May form combustible dust concentrations in air

Precautionary Statements: P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362

Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse.

Other References

Merck
14,6100
Beilstein
113951
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
QT1925000

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