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89-57-6 - 5-Aminosalicylic acid, 95% - 5-Amino-2-hydroxybenzoic acid - Mesalamine - B23970 - Alfa Aesar

B23970 5-Aminosalicylic acid, 95%

CAS Number
89-57-6
Synonyms
5-Amino-2-hydroxybenzoic acid
Mesalamine

Size Price ($) Quantity Availability
100g 49.50
500g 154.00
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5-Aminosalicylic acid, 95%

MDL
MFCD00007877
EINECS
201-919-1

Chemical Properties

Formula
C7H7NO3
Formula Weight
153.14
Melting point
ca 280° dec.
Solubility
Soluble in dimethyl sulfoxide.

Applications

5-Aminosalicylic acid is used in the preparation of gastrointestinal anti-inflammatory agents. It is a metabolite of sulfasalazine. It acts as a drug involved in the treatment of Crohn’s disease and ulcerative colitis. Further, it is used to make dyes and light-sensitive papers.

Notes

Moisture, air and light sensitive. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides and chloroformates.

Literature References

Bijani, S.; Jain, V.; Padmanabhan, D.; Pandey, B.; Shah, A. Mixed Pd/C and Pt/C as efficient catalysts for deuteration of Mesalamine. Tetrahedron Lett. 2015, 56 (10), 1211-1214.

Goyanes, A.; Buanz, A. B. M.; Hatton, G. B.; Gaisford, S.; Basit, A. W. 3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets. Eur. J. Pharm. Biopharm. 2015, 89, 157-162.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5904
Beilstein
2090421
Harmonized Tariff Code
2922.50
TSCA
Yes
RTECS
VO1400000

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