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B23970 5-Aminosalicylic acid, 95%

CAS Number
89-57-6
Synonyms
5-Amino-2-hydroxybenzoic acid
Mesalamine

Stock No. Size Price ($) Quantity Availability
B23970-22 100g 51.50
B23970-36 500g 161.00
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5-Aminosalicylic acid, 95%

MDL
MFCD00007877
EINECS
201-919-1

Chemical Properties

Formula
C7H7NO3
Formula Weight
153.14
Melting point
ca 280° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in dimethyl sulfoxide.

Applications

5-Aminosalicylic acid is used in the preparation of gastrointestinal anti-inflammatory agents. It is a metabolite of sulfasalazine. It acts as a drug involved in the treatment of Crohn’s disease and ulcerative colitis. Further, it is used to make dyes and light-sensitive papers.

Notes

Moisture, air and light sensitive. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides and chloroformates.

Literature References

Bijani, S.; Jain, V.; Padmanabhan, D.; Pandey, B.; Shah, A. Mixed Pd/C and Pt/C as efficient catalysts for deuteration of Mesalamine. Tetrahedron Lett. 2015, 56 (10), 1211-1214.

Goyanes, A.; Buanz, A. B. M.; Hatton, G. B.; Gaisford, S.; Basit, A. W. 3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets. Eur. J. Pharm. Biopharm. 2015, 89, 157-162.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,5904
Beilstein
2090421
Harmonized Tariff Code
2922.50
TSCA
Yes
RTECS
VO1400000

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