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694-85-9 - 1-Methyl-2-pyridone, 99+% - B24244 - Alfa Aesar

B24244 1-Methyl-2-pyridone, 99+%

CAS Number
694-85-9
Synonyms

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1-Methyl-2-pyridone, 99+%

MDL
MFCD00006520
EINECS
211-777-2

Chemical Properties

Formula
C6H7NO
Formula Weight
109.13
Boiling Point
249-251°
Flash Point
>110°(230°F)
Density
1.112
Refractive Index
1.5690
Solubility
Soluble in water (1000 mg/ml at 20°C).

Applications

1-Methyl-2-pyridone is used in pharmaceutical industry. A common problem with hydrophobic non-natural base pairs—the inefficient extension following such a base pair—is reduced by using the methylpyridone scaffold, which simultaneously limits another frequent problem of non-natural bases: mispairs with deoxyadenosine.

Notes

Store at room temperature. Incompatible with oxidizing agents.

Literature References

J Shailaja, S Karthikeyan.; V Ramamurthy. Cyclodextrin mediated solvent-free enantioselective photocyclization of N-alkyl pyridones.Tetrahedron Lett. 2002, 43 (51),9335-9339 .

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
107805
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
UV1148100

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