1-Bromo-2,3,5,6-tetrafluorobenzene is used to produce 1,2,4,5-tetrafluoro-3-hept-1-ynyl-benzene. It is also used as a pharmaceutical intermediate.
GB Deacon and DG Vince. Symmetrization of Bromobis(polyfluorophenyl)thallium(III) compounds with copper powder. Australian Journal of Chemistry. 1975, 28 (9), 1931 - 1941.
Zongjun Qiao; Hui Liu; Xiao Xiao; Yana Fu; Jianpeng Wei; Yuxue Li; and Xuefeng Jiang. Efficient Access to 1,4-Benzothiazine: Palladium-Catalyzed Double C-S Bond Formation Using Na2S2O3 as Sulfurating Reagent. Org. Lett. 2013, 15 (11), 2594-2597.
Hazard Statements: H226-H315-H319-H335
Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P280g-P305+P351+P338
Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.