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Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.
Young Hye Kim; Se Hoon Choi; Carla D'Avanzo; Matthias Hebisch; Christopher Sliwinski; Enjana Bylykbashi; Kevin J Washicosky; Justin B Klee; Oliver Brüstle; Rudolph E Tanzi; Doo Yeon Kim. A 3D human neural cell culture system for modeling Alzheimer's disease. Nature Protocols. 2015, 10 (7), 985-1006.
D P Penney; J M Powers; M Frank; C Willis; C Churukian. Analysis and testing of biological stains--the Biological Stain Commission Procedures. Biotechnic and Histochemistry. 2002, 77 (5-6), 237-275.
Hazard Statements: H350-H361
May cause cancer. Suspected of damaging fertility or the unborn child.
Precautionary Statements: P201-P280-P202-P308+P313-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.