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The tetramer of HCN. Useful precursor of various heterocycles, e.g. imidazoles: Synthesis, 767 (1988); J. Org. Chem., 39, 2341 (1974), pyrazines: J. Org. Chem., 39, 2341 (1974); 44, 827, 4871 (1979); J. Heterocycl. Chem., 11, 79 (1974); Heterocycles, 16, 1449 (1981), pteridines: J. Heterocycl. Chem., 23, 1299 (1986). For extension to synthesis of nucleosides, see: J. Org. Chem., 50, 747 (1985). For a review, with particular reference to its utility in heterocyclic synthesis, see: Tetrahedron, 59, 2749 (2003)./n
Hazard Statements: H301-H312+H332
Toxic if swallowed. Harmful in contact with skin. Harmful if inhaled.
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P312-P330-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant