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3,5,5-Trimethyloxazolidine-2,4-dione is used in the control of absence (petit mal) seizures that are refractory to treatment with other medications. It is used in the treatment of epilepsy.
N Kurata; Y Nishimura; M Iwase; N E Fischer; B K Tang; T Inaba; H Yasuhara. Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1. Xenobiotica. 1998, 28 (11), 1041-1047.
E Tanaka; M Terada; S Misawa. Cytochrome P450 2E1: its clinical and toxicological role. Journal of Clinical Pharmacy and Therapeutics. 2000, 25 (3), 165-175.
Hazard Statements: H360
May damage fertility or the unborn child.
Precautionary Statements: P201-P202-P281-P308+P313-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant