2-Chloropropionyl chloride is used as a reagent in the chemical surface fictionalization of parylene C. It is used in the synthesis of (±)-mintlactone, in the preparation of a poly(ethylene glycol) macro initiator & chlorine modified TiO2 nanoparticles, the ATRP initiators.
Paulin N Wahjudi; Jin H Oh; Salam O Salman; Jason A Seabold; Damien C Rodger; Yu-Chong Tai; Mark E Thompson. Improvement of metal and tissue adhesion on surface-modified parylene C. Journal of Biomedical Materials Research, Part A. 2009, 89 (1), 206-214.
Krzysztof Matyjaszewski; Jen-Lung Wang; Thomas Grimaud and Devon A. Shipp. Controlled/Living Atom Transfer Radical Polymerization of Methyl Methacrylate Using Various Initiation Systems. Macromolecules. 1998, 31 (5), 1527-1534.
Hazard Statements: H226-H302-H314-H318
Flammable liquid and vapour. Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.