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2-Chloropropionyl chloride is used as a reagent in the chemical surface fictionalization of parylene C. It is used in the synthesis of (±)-mintlactone, in the preparation of a poly(ethylene glycol) macro initiator & chlorine modified TiO2 nanoparticles, the ATRP initiators.
Paulin N Wahjudi; Jin H Oh; Salam O Salman; Jason A Seabold; Damien C Rodger; Yu-Chong Tai; Mark E Thompson. Improvement of metal and tissue adhesion on surface-modified parylene C. Journal of Biomedical Materials Research, Part A. 2009, 89 (1), 206-214.
Krzysztof Matyjaszewski; Jen-Lung Wang; Thomas Grimaud and Devon A. Shipp. Controlled/Living Atom Transfer Radical Polymerization of Methyl Methacrylate Using Various Initiation Systems. Macromolecules. 1998, 31 (5), 1527-1534.
Hazard Statements: H226-H302-H314-H335
Flammable liquid and vapour. Harmful if swallowed. Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant