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Methyl benzenesulfonate is a sulfonate ester which acts as a potential genotoxic impurity in drug substances. Further, it exerts genotoxic effects in bacterial and mammalian cell systems.
Giricheva, N. I.; Fedorov, M. S.; Girichev, G. V. Conformations of methylbenzenesulfonate and its substituted derivatives: gas-phase electron diffraction versus vibrational spectroscopy. Struct. Chem. 2015, 26 (5), 1543-1553.
Zhang, X.; Jiang, X.; Li, Y.; Lin, Z.; Zhang, G.; Wu, Y. Synthesis, crystal structures and properties of new quinolinium derivatives. Chem. Phys. Lett. 2015, 641, 141-145.
Hazard Statements: H302-H314-H341
Harmful if swallowed. Causes severe skin burns and eye damage. Suspected of causing genetic defects.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.