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1-Indanol derivative was found to be an efficient ligand for the palladium-catalyzed asymmetric Heck reaction. It is used as pharmaceutical intermediate.
Jonas Altnöder; Aude Bouchet; Juhyon J Lee; Katharina E Otto; Martin A Suhm; Anne Zehnacker-Rentien. Chirality-dependent balance between hydrogen bonding and London dispersion in isolated (±)-1-indanol clusters. Physical Chemistry Chemical Physics. 2013, 15 (25), 10167-10180.
Attila Felinger; Dongmei Zhou; Georges Guiochon. Determination of the single component and competitive adsorption isotherms of the 1-indanol enantiomers by the inverse method. Journal of Chromatography A. 2003, 1005 (1-2), 35-49.
Oxidation to the indanone can be effected with acetone in the presence of K2CO3, catalyzed by Dichlorotris(triphenylphosphine)ruthenium(II), L00373: J. Chem. Soc., Chem. Commun., 337 (1992).
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.