5,6-Diphenyl-3-(2-pyridyl)-1,2 4-triazine is widely utilized as a reagent for the determination of sub microgram levels of iron in serum. It is also used for the simultaneous determination of iron and copper.
Reagent for the determination of Cu, and for the spectrophotometric determination of Fe(II) and Ru(II): Anal. Chem., 46, 992 (1974); Anal. Chim. Acta, 78, 423 (1975)./n
Yamada, M.; Muto, Y.; Kurihara, H.; Slanina, Z.; Suzuki, M.; Maeda, Y.; Rubin, Y.; Olmstead, M. M.; Balch, A. L.; Nagase, S.; Lu, X.; Akasaka, T. Regioselective Cage Opening of La2@D2(10611)-C72 with 5,6-Diphenyl-3-(2-pyridyl)-1,2,4-triazine. Angew. Chem. Int. Ed. 2015, 54 (7), 2232-2235.
Anjomshoa, M.; Hadadzadeh, H.; Mahani, M. T.; Fatemi, S. J.; Sardou, M. A.; Rudbari, H. A.; Nardo, V. M. A mononuclear Cu(II) complex with 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine: Synthesis, crystal structure, DNA- and BSA-binding, molecular modeling, and anticancer activity against MCF-7, A-549, and HT-29 cell lines. Angew. Chem. Int. Ed. 2015, 96, 66-82.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.