It is used as a reagent for palladium catalyzed Suzuki-Miyaura coupling reactions, Pd-catalyzed homocouplings, Rhodium(I)-catalyzed 1,4-addition reactions. It is used in the preparation of protein kinase inhibitors, G Protein-Coupled Receptor.
Linglin Wu; Emma Drinkel; Fiona Gaggia; Samanta Capolicchio; Anthony Linden; Laura Falivene; Luigi Cavallo; Reto Dorta. Room-temperature synthesis of tetra-ortho-substituted biaryls by NHC-catalyzed Suzuki-Miyaura couplings. Chemistry: A European Journal. 2011, 17 (46), 12886-12890.
Srimanta Manna; Soham Maity; Sujoy Rana; Soumitra Agasti; Debabrata Maiti. ipso-Nitration of arylboronic acids with bismuth nitrate and perdisulfate. Organic Letters. 2012, 14 (7), 1736-1739.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.