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It is used as a reagent for palladium catalyzed Suzuki-Miyaura coupling reactions, Pd-catalyzed homocouplings, Rhodium(I)-catalyzed 1,4-addition reactions. It is used in the preparation of protein kinase inhibitors, G Protein-Coupled Receptor.
Linglin Wu; Emma Drinkel; Fiona Gaggia; Samanta Capolicchio; Anthony Linden; Laura Falivene; Luigi Cavallo; Reto Dorta. Room-temperature synthesis of tetra-ortho-substituted biaryls by NHC-catalyzed Suzuki-Miyaura couplings. Chemistry: A European Journal. 2011, 17 (46), 12886-12890.
Srimanta Manna; Soham Maity; Sujoy Rana; Soumitra Agasti; Debabrata Maiti. ipso-Nitration of arylboronic acids with bismuth nitrate and perdisulfate. Organic Letters. 2012, 14 (7), 1736-1739.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant