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B24628 Isobutyrophenone, 97%

CAS Number
611-70-1
Synonyms
Isopropyl phenyl ketone

Stock No. Size Price ($) Quantity Availability
B24628-14 25g 38.00
B24628-22 100g 84.60
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Isobutyrophenone, 97%

MDL
MFCD00008917
EINECS
210-275-0

Chemical Properties

Formula
C10H12O
Formula Weight
148.21
Melting point
Boiling Point
217°
Flash Point
84°(184°F)
Density
0.988
Refractive Index
1.5170
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in alcohol. Insoluble in water.

Applications

Isobutyrophenone is used as an internal standard in the determination of hydroxyzine hydrochloride and benzyl alcohol in injection solutions. It is also used in the preparation of alpha-hydroxyisobutyrophenone. Isobutyrophenone is employed as photosensitizer intermediate. It can react with bromoacetic acid ethyl ester to get 3-hydroxy-4-methyl-3-phenyl-valeric acid ethyl ester.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

G N Menon.; B J Norris. Simultaneous determination of hydroxyzine hydrochloride and benzyl alcohol in injection solutions by high-performance liquid chromatography. Journal of Pharmaceutical Sciences. 1981, 70(6), 697-698.

Guthrie JP.; Cossar J. The chlorination of isobutyrophenone: determination of its p K a value and of the course of the reaction. Can. J. Chem. 1990, 68(3) 397-4036.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H315-H319

Combustible liquid. Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2914.39
TSCA
Yes

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