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399-51-9 - 6-Fluoroindole, 98% - B24633 - Alfa Aesar

B24633 6-Fluoroindole, 98%

CAS Number
399-51-9
Synonyms

Size Price ($) Quantity Availability
1g 73.90
5g 258.00
25g 931.00
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6-Fluoroindole, 98%

MDL
MFCD00056933
EINECS
000-000-0

Chemical Properties

Formula
C8H6FN
Formula Weight
135.14
Melting point
74-77°
Sensitivity
Light Sensitive
Solubility
Insoluble in water.

Applications

6-Fluoroindole acts as a reagent in the synthesis of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, which acts as a potential anticancer immunomodulator. It is also employed as an antifungal and antibacterial agent. Further, it serves as a potent selective serotonin reuptake inhibitor. In addition to this, it is used as a inhibitor of HIV-1 attachment.

Notes

Light sensitive. Store in a cool place.Incompatible with strong oxidizing agents, strong reducing agents, strong acids and strong bases.

Literature References

Samanta, R.; Narayan, R.; Bauer, J. O.; Strohmann, C.; Sievers, S.; Antonchick, A. P. Oxidative regioselective amination of chromones exposes potent inhibitors of the hedgehog signaling pathway. Chem. Commun. 2015, 51 (5), 925-928.

Hayashi, R.; Ohmori, E.; Moriwaki, M.; Kumagai, H.; Isogaya, M. Indolylpiperidine derivatives as potent and selective alpha1B adrenoceptor antagonists. Bioorg. Med. Chem. Lett. 2015, 25 (18), 3921-3923.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
112192
Harmonized Tariff Code
2933.99
TSCA
No

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