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78-98-8 - Pyruvic aldehyde, 35-45% w/w aq. soln - Methylglyoxal - Pyruvaldehyde - B24664 - Alfa Aesar

B24664 Pyruvic aldehyde, 35-45% w/w aq. soln

CAS Number
78-98-8
Synonyms
Methylglyoxal
Pyruvaldehyde

Size Price ($) Quantity Availability
25g 34.11
100g 53.73
500g 168.30
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Pyruvic aldehyde, 35-45% w/w aq. soln

MDL
MFCD00006960
EINECS
201-164-8

Chemical Properties

Formula
C3H4O2
Formula Weight
72.06
Density
1.2
Refractive Index
1.4050
Sensitivity
Air Sensitive
Solubility
Soluble in DMSO, water.

Applications

Pyruvic aldehyde is used in the synthesis and cytotoxicity evaluation of N-terminal analogues of tubulysin-U an antimitotic compound. Also used in the synthesis of imidazoles as potent calcitonin gene-related CGRP antagonists.

Notes

Air sensitive. Store under dry inert gas. Store away from oxidizing agents, air.

Literature References

Paul J Beisswenger; Keith S Drummond; Robert G Nelson; Scott K Howell; Benjamin S Szwergold; Michael Mauer. Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress. Diabetes. 2005, 54 (11), 3274-3281.

Katrien H J Gaens; Coen D A Stehouwer; Casper G Schalkwijk. Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity. Current Opinion in Lipidology. 2013, 24 (1), 4-11.

GHS Hazard and Precautionary Statements

Hazard Statements: H318-H290-H341-H302-H317

Causes serious eye damage. May be corrosive to metals. Suspected of causing genetic defects. Harmful if swallowed. May cause an allergic skin reaction.

Precautionary Statements: P201-P261-P280-P281-P305+P351+P338-P310-P301+P312-P405-P406-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in corrosive resistant container with a resistant inner liner. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6081
Beilstein
906750
Harmonized Tariff Code
2914.40
TSCA
Yes
RTECS
UZ0700000

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