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B24664 Pyruvic aldehyde, 35-45% w/w aq. soln

CAS Number
78-98-8
Synonyms
Methylglyoxal
Pyruvaldehyde

Stock No. Size Price ($) Quantity Availability
B24664-14 25g 21.80
B24664-22 100g 62.10
B24664-36 500g 195.00
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Pyruvic aldehyde, 35-45% w/w aq. soln

MDL
MFCD00006960
EINECS
201-164-8

Chemical Properties

Formula
C3H4O2
Formula Weight
72.06
Density
1.2
Refractive Index
1.4050
Storage & Sensitivity
Air Sensitive. Store under Argon. Ambient temperatures.
Solubility
Soluble in DMSO, water.

Applications

Pyruvic aldehyde is used in the synthesis and cytotoxicity evaluation of N-terminal analogues of tubulysin-U an antimitotic compound. Also used in the synthesis of imidazoles as potent calcitonin gene-related CGRP antagonists.

Notes

Air sensitive. Store under dry inert gas. Store away from oxidizing agents, air.

Literature References

Paul J Beisswenger; Keith S Drummond; Robert G Nelson; Scott K Howell; Benjamin S Szwergold; Michael Mauer. Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress. Diabetes. 2005, 54 (11), 3274-3281.

Katrien H J Gaens; Coen D A Stehouwer; Casper G Schalkwijk. Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity. Current Opinion in Lipidology. 2013, 24 (1), 4-11.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H302-H317-H318-H341

Combustible liquid. Harmful if swallowed. May cause an allergic skin reaction. Causes serious eye damage. Suspected of causing genetic defects.

Precautionary Statements: P201-P202-P210-P261-P264b-P270-P272-P280g-P281-P301+P312-P302+P352-P305+P351+P338-P308+P313-P310-P330-P333+P313-P363-P370+P378q-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. If skin irritation or rash occurs: Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,6081
Beilstein
906750
Harmonized Tariff Code
2914.40
TSCA
Yes
RTECS
UZ0700000

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