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(R)-(+)-2-Pyrrolidinone-5-carboxylic acid serves as a building block in the synthesis of diphthamide.
Bing Yan; Hai-Feng Lu. Lanthanide-centered inorganic/organic hybrids from functionalized 2-pyrrolidinone-5-carboxylic acid bridge: Covalently bonded assembly and luminescence. Journal of Organometallic Chemistry. 2009, 694 (16), 2597-2603.
Masahito Ochiai, Minako Inenaga; Yoshimitsu Nagao Robert M. Moriarty; Radhe K Vaid; Michael P. Duncan. Oxidative decarboxylation of cyclic amino acids and dehydrogenation of cyclic secondary amines with iodosobenzene. Tetrahedron Letters. 1988, 29 (52), 6917-6920.
For applications, see next entry.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.