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(R)-(+)-2-Pyrrolidinone-5-carboxylic acid serves as a building block in the synthesis of diphthamide.
Bing Yan; Hai-Feng Lu. Lanthanide-centered inorganic/organic hybrids from functionalized 2-pyrrolidinone-5-carboxylic acid bridge: Covalently bonded assembly and luminescence. Journal of Organometallic Chemistry. 2009, 694 (16), 2597-2603.
Masahito Ochiai, Minako Inenaga; Yoshimitsu Nagao Robert M. Moriarty; Radhe K Vaid; Michael P. Duncan. Oxidative decarboxylation of cyclic amino acids and dehydrogenation of cyclic secondary amines with iodosobenzene. Tetrahedron Letters. 1988, 29 (52), 6917-6920.
For applications, see next entry.
Hazard Statements: H315-H318-H335
Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant