Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

1892-57-5 - 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 98% - N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide - B25057 - Alfa Aesar

B25057 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 98%

CAS Number
1892-57-5
Synonyms
N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide

Size Price ($) Quantity Availability
5g 79.21
25g 272.95
100g 1001.16
Add to Cart Add to Quote Request View Item

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 98%

MDL
MFCD00044916
EINECS
217-579-2

Chemical Properties

Formula
C8H17N3
Formula Weight
155.24
Boiling Point
66-68°/1mm
Flash Point
>110°(230°F)
Density
0.885
Refractive Index
1.4610
Sensitivity
Air & Moisture Sensitive
Solubility
Soluble in water.

Applications

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Notes

Air sensitive. Incompatible with strong acids and strong oxidizing agents.

Literature References

Free base form of 'Water-soluble' carbodiimide. For applications see following entry. In the presence of CuCl2, (E)- or (Z)-2-substituted 3-hydroxy-3-phenylpropionate esters can be dehydrated stereoselectively to the corresponding (E) or (Z)-cinnamates: Tetrahedron Lett., 40, 5019 (1999).

Li, J.; Yue, L.; Li, C.; Pan, Y.; Yang, L. Enantioselectivity and catalysis improvements of Pseudomonas cepacia lipase with Tyr and Asp modification. Catal. Sci. Technol. 2015, 5, 2681-2687.

Lopez, R. J.; Babanova, S.; Artyushkova, K.; Atanassov, P. Surface modifications for enhanced enzyme immobilization and improved electron transfer of PQQ-dependent glucose dehydrogenase anodes. Bioelectrochemistry 2015, 105, 78-87.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
507429
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2925.19
TSCA
Yes

Recommended

  • A10312

    N-Hydroxysuccinimide, 98+%
  • A10973

    N,N'-Dicyclohexylcarbodiimide, 99%
  • A13016

    4-(Dimethylamino)pyridine, 99%
  • A14547

    p-Toluenesulfonyl chloride, 98%
  • 43997

    N,N-Dimethylformamide, anhydrous, 99.8%, packaged under Argon in resealable ChemSeal™ bottles

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware