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37622-90-5 - Ethyl 1H-pyrazole-4-carboxylate, 98% - 1H-Pyrazole-4-carboxylic acid ethyl ester - B25351 - Alfa Aesar

B25351 Ethyl 1H-pyrazole-4-carboxylate, 98%

CAS Number
37622-90-5
Synonyms
1H-Pyrazole-4-carboxylic acid ethyl ester

Size Price ($) Quantity Availability
1g 38.70
5g 138.00
25g 560.00
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Ethyl 1H-pyrazole-4-carboxylate, 98%

MDL
MFCD00010844

Chemical Properties

Formula
C6H8N2O2
Formula Weight
140.14
Melting point
75-80°
Boiling Point
138-140°/3mm
Solubility
Miscible with acetone.

Applications

Ethyl 1H-pyrazole-4-carboxylate is used in the preparation of isoxazole-4-carboxylic acid derivatives and isoxazole-3,5-dicarboxamides. Further, it acts as an intermediate in organic synthesis.

Notes

Incompatible with strong oxidizing agents, strong acids and bases.

Literature References

Zheng, K.; Iqbal, S.; Hernandez, P.; Park, H.; LoGrasso, P. V.; Feng, Y. Design and Synthesis of Highly Potent and Isoform Selective JNK3 Inhibitors: SAR Studies on Aminopyrazole Derivatives. J. Med. Chem. 2014, 57 (23), 10013-10030.

Mane, R. S.; Sasaki, T.; Bhanage, B. M. Silica supported palladium-phosphine as a reusable catalyst for alkoxycarbonylation and aminocarbonylation of aryl and heteroaryl iodides. RSC Adv. 2015, 5 (115), 94776-94785.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.19
TSCA
No

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