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B25412 Papaverine hydrochloride, 99%

CAS Number
61-25-6
Synonyms
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride

Stock No. Size Price ($) Quantity Availability
B25412-06 5g 32.70
B25412-14 25g 89.50
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Papaverine hydrochloride, 99%

MDL
MFCD00012745
EINECS
200-502-1

Chemical Properties

Formula
C20H21NO4•HCl
Formula Weight
375.85
Melting point
ca 220° dec.
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in water (50 mg/ml), DMSO, methanol, 100% ethanol and chloroform.

Applications

Papaverine hydrochloride is used as a smooth muscle relaxant, with noted treatment for impotence. It can also act as a cerebral vasodilator through the possible inhibition of PDE (phosphodiesterases) and/or calcium channel actions.

Notes

Light sensitive. Incompatible with oxidizing agents.

Literature References

H.W.Jayne; P.Scheinberg; M.Rich; M.S.Belle; Ione Blackburn. The effect of intravenous papaverine hydrochloride on the cerebral circulation. J Clin Invest. 1952, 31,(1), 111-114.

 

John S.Meyer, MD; Fumio Gotoh, MD; John Gilroy, MD; Nasaharu Nara, MD. Improvement in brain oxygenation and clinical improvement in patients with strokes treated with papaverine hydrochloride. JAMA. 1965, 194,(9), 957-961.

GHS Hazard and Precautionary Statements

Hazard Statements: H301

Toxic if swallowed.

Precautionary Statements: P264b-P270-P301+P310-P330-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,7019
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2939.19
TSCA
Yes
RTECS
NW8575000

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