Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

108-73-6 - Phloroglucinol, anhydrous, 98% - 1,3,5-Trihydroxybenzene - 1,3,5-Benzenetriol, anhydrous - B25502 - Alfa Aesar

B25502 Phloroglucinol, anhydrous, 98%

CAS Number
108-73-6
Synonyms
1,3,5-Trihydroxybenzene
1,3,5-Benzenetriol, anhydrous

Size Price ($) Quantity Availability
50g 47.00
250g 183.00
Add to Cart Add to Quote Request View Item

Phloroglucinol, anhydrous, 98%

MDL
MFCD00002286
EINECS
203-611-2

Chemical Properties

Formula
C6H6O3
Formula Weight
126.11
Melting point
215-220°
Sensitivity
Light Sensitive & Hygroscopic
Solubility
Soluble in diethyl ether, ethanol and pyridine.

Applications

Reagent for pentoses, pentosans and aldehydes. Used as a bone decalcifier in microscopy specimens.Phloroglucinol is mainly used as a coupling agent in printing. It is an active component of Tollen’s reagent and Gunzburg reagent used to test pentoses and hydrochloric acid in gastric juice respectively. In analytical chemistry, it is used to study condensed tannins by means of depolymerization. It is also involved in the synthesis of 2,4,6-triamino-1,3,5- trinitrobenzene, trinitrophloroglucinol and pharmaceuticals like flopropione .

Notes

Incompatible with acid chlorides, acid anhydrides, bases and oxidizing agents.

Literature References

Reacts with mono- or dimethylamine in DMF-water, with displacement of one of the OH groups, to give 5-aminoresorcinols: Helv. Chim. Acta, 56, 510 (1973).

The electron-rich nucleus undergoes acylation with nitriles under mild Lewis acid catalysis, to give ketones (Houben-Hoesch reaction).

Selective monobromination cannot be achieved conventionally. For bromination-debromination protocols for the preparation of the mono- and di-brominated derivatives, see: Can. J. Chem., 67, 335 (1989).

Dubey, R.; Desiraju, G. R. Combinatorial Crystal Synthesis: Structural Landscape of Phloroglucinol: 1, 2-bis (4-pyridyl) ethylene and Phloroglucinol: Phenazine. Angew. Chem. Int. Ed. 2014, 53 (48), 13178-13182.

Ghimbeu, C. M.; Vidal, L.; Delmotte, L.; Le Meins, J. M.; Vix-Guterl, C. Catalyst-free soft-template synthesis of ordered mesoporous carbon tailored using phloroglucinol/glyoxylic acid environmentally friendly precursors. Green Chem. 2014, 16 (6), 3079-3088.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,7328
Beilstein
1341907
Harmonized Tariff Code
2907.29
TSCA
Yes
RTECS
SY1050000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware