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1196-69-6 - Indole-5-carboxaldehyde, 98% - 5-Formylindole - B25517 - Alfa Aesar

B25517 Indole-5-carboxaldehyde, 98%

CAS Number
1196-69-6
Synonyms
5-Formylindole

Size Price ($) Quantity Availability
1g 39.04
5g 149.35
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Indole-5-carboxaldehyde, 98%

MDL
MFCD02093664

Chemical Properties

Formula
C9H7NO
Formula Weight
145.16
Melting point
96-100°
Sensitivity
Air Sensitive
Solubility
Insoluble in water.

Applications

Indole-5-carboxaldehyde is used as a reactant in preparation of curcumin derivatives as anti-proliferative & anti-inflammatory agents; and in synthesis of para-para stilbenophanes by McMurry coupling. It is also used as a reactant in stereoselective synthesis of dibenzylideneacetone derivatives as β-amyloid imaging probes and in structure-based drug design of aurora kinase A inhibitors.

Notes

Air sensitive. Incompatible with oxidizing agents.

Literature References

A.M.Katsori; M.Chatzopoulou; K.Dimas; C.Kontogiorgis; A.Patsilinakos; T.Trangas; D.Hadjipavlou-Litina. Curcumin analogues as possible anti-proliferative & anti-inflammatory agents. European Journal of Medicinal Chemistry. 2011, 46,(7), 2722-2735.

 

Raquel Alvarez; Vilmari Lopez; Carmen Mateo; Manuel Medarde. New para-para stilbenophanes: synthesis by McMurry coupling, conformational analysis and inhibition of tubulin polymerisation. Chemistry: A European Journal. 2011, 17,(12), 3406-3419.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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