Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

3680-69-1 - 6-Chloro-7-deazapurine, 98% - 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine - B25713 - Alfa Aesar

B25713 6-Chloro-7-deazapurine, 98%

CAS Number
3680-69-1
Synonyms
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

Size Price ($) Quantity Availability
1g 274.00
5g 1077.00
Add to Cart Add to Quote Request View Item

6-Chloro-7-deazapurine, 98%

MDL
MFCD01686865

Chemical Properties

Formula
C6H4ClN3
Formula Weight
153.52
Melting point
190-192°
Solubility
Soluble in DMSO, ethyl acetate and methanol.

Applications

6-Chloro-7-deazapurine is used for making tofacitinib.

Notes

Store in cool, dry place in a well sealed container. Store away from oxidizing agents.

Literature References

Helmut Rosemeyer and Frank Seela. Stereoselective synthesis of pyrrolo[2,3-d]pyrimidine α- and β-D-ribonucleosides from anomerically pure D-ribofuranosyl chlorides: Solid-Liquid Phase-Transfer Glycosylation and 15N-NMR Spectra. Helvetica Chimica Acta. 1988, 71 (6), 1573-1585.

Balakumar Arumugham; Hyo-Joong Kim; Mark N. Prichard; Earl R. Kern; Chung K. Chu. Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus). Bioorganic & Medicinal Chemistry Letters. 2006, 16 (2), 285-287.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.59
TSCA
No

Recommended

  • 43176

    Triethylgermanium hydride, 97%
  • 36675

    Potassium permanganate, low in mercury, ACS, 99.0% min
  • H54792

    1-(2-Mesitylenesulfonyl)-3-nitro-1H-1,2,4-triazole, 99+%
  • J67469

    Minocycline hydrochloride, 50 mg/ml in distilled water, sterile-filtered
  • 41638

    Tungsten sputtering target, 50.8mm (2.0in) dia x 3.18mm (0.125in) thick, 99.95% (metals basis)

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware